A Comprehensive Review on Biopolymer Mediated Nanomaterial Composites and Their Applications in Electrochemical Sensors
Vasudevan, Mugashini and Perumal, Veeradasan and Karuppanan, Saravanan and Ovinis, Mark and Raja, Pandian Bothi and Gopinath, Subash C. B. and Edison, Thomas Nesakumar Jebakumar Immanuel (2022) A Comprehensive Review on Biopolymer Mediated Nanomaterial Composites and Their Applications in Electrochemical Sensors. Critical Reviews in Analytical Chemistry. ISSN 1040-8347
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Abstract
Biopolymers are an attractive green alternative to conventional polymers, owing to their excellent biocompatibility and biodegradability. However, their amorphous and nonconductive nature limits their potential as active biosensor material/substrate. To enhance their bio-analytical performance, biopolymers are combined with conductive materials to improve their physical and chemical characteristics. We review the main advances in the field of electrochemical biosensors, specifically the structure, approach, and application of biopolymers, as well as their conjugation with conductive nanomaterials, polymers, and metal oxides in green-based non-invasive analytical biosensors. In addition, we reviewed signal measurement, substrate bio-functionality, biochemical reaction, sensitivity, and limit of detection (LOD) of different biopolymers on various transducers. To date, pectin biopolymer, when conjugated with either gold nanoparticles, polypyrrole, reduced graphene oxide, or multiwall carbon nanotubes forming nanocomposites on glass carbon electrode transducer, tends to give the best LOD, highest sensitivity, and can detect multiple analytes/targets. This review will spur new possibilities for the use of biosensors for medical diagnostic tests.
| Item Type: | Article | ||||||
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| Identification Number: | https://doi.org/10.1080/10408347.2022.2135090 | ||||||
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| Uncontrolled Keywords: | Biopolymers, high-performance detection, nanosensors, sensing elements | ||||||
| Subjects: | CAH10 - engineering and technology > CAH10-01 - engineering > CAH10-01-02 - mechanical engineering | ||||||
| Divisions: | Faculty of Computing, Engineering and the Built Environment > School of Engineering and the Built Environment > Dept. of Engineering | ||||||
| Depositing User: | Mark Ovinis | ||||||
| Date Deposited: | 23 Jun 2023 13:38 | ||||||
| Last Modified: | 26 Oct 2023 03:00 | ||||||
| URI: | https://www.open-access.bcu.ac.uk/id/eprint/14495 |
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