Pregabalin Assay in a Patient with Widespread Neuropathic Pain and Late Onset Gluten Intolerance
Hanu-Cernat, D.E. and Phipps, A.N. and Raphael, J.H. (2011) Pregabalin Assay in a Patient with Widespread Neuropathic Pain and Late Onset Gluten Intolerance. Pain Medicine, 12 (8). pp. 1262-1266. ISSN 15262375 (ISSN)
Full text not available from this repository. (Request a copy)Abstract
Objective. The aim of this study was to determine the pharmacokinetics of pregabalin in a patient with malabsorption secondary to celiac disease and compare the findings with the data available from pre-existing studies in healthy volunteer controls. Methods. A 39-year-old man consented to a 24-hour pregabalin assay with sequential pre and post-dose blood sampling. Results. The blood levels measured in this subject were no different to healthy male volunteers enrolled in previous studies. Conclusion. Although the results obtained are encouraging, the wide spectrum of effects and interactions of various drugs in malabsorption would suggest that therapy of any kind should be considered at individual level and monitored with blood assays. Wiley Periodicals, Inc.
| Item Type: | Article | ||||
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| Identification Number: | https://doi.org/10.1111/j.1526-4637.2011.01165.x | ||||
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| Uncontrolled Keywords: | Celiac Disease, Neuropathic Pain, Pharmacokinetics, Pregabalin, buprenorphine, codeine, gabapentin, glucose, immunoglobulin A, immunoglobulin G, opiate, paracetamol, pregabalin, tramadol, add on therapy, adult, article, blood sampling, bone densitometry, case report, celiac disease, clinical feature, drowsiness, drug absorption, drug blood level, drug determination, drug efficacy, drug half life, drug mechanism, dysesthesia, gluten free diet, glycemic control, human, human tissue, male, neuropathic pain, spinal pain, thoracic spinal cord, treatment response, weight reduction, Adult, Analgesics, Animals, Celiac Disease, gamma-Aminobutyric Acid, Humans, Male, Neuralgia | ||||
| Subjects: | CAH01 - medicine and dentistry > CAH01-01 - medicine and dentistry > CAH01-01-01 - medical sciences (non-specific) | ||||
| Divisions: | Faculty of Health, Education and Life Sciences > School of Nursing and Midwifery | ||||
| Depositing User: | Hussen Farooq | ||||
| Date Deposited: | 25 Feb 2017 14:43 | ||||
| Last Modified: | 12 Jan 2022 11:13 | ||||
| URI: | https://www.open-access.bcu.ac.uk/id/eprint/2110 |
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