The identification and measurement of autistic features in children with septo-optic dysplasia, optic nerve hypoplasia and isolated hypopituitarism

Jutley-Neilson, J. and Harris, G. and Kirk, J. (2013) The identification and measurement of autistic features in children with septo-optic dysplasia, optic nerve hypoplasia and isolated hypopituitarism. Research in Developmental Disabilities, 34 (12). pp. 4310-4318. ISSN 08914222 (ISSN)

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Abstract

This study aimed to highlight the occurrence of autism spectrum disorders (ASDs) in children with septo-optic dysplasia (SOD) and optic nerve hypoplasia (ONH). A cross-sectional study was designed, including 28 children with SOD and 14 children with ONH. Clinician diagnosis of ASD was reported in 14 children. The Social Communication Questionnaire (SCQ) reported that 23 children met the cut-off point for ASD, and 9 children met the cut-off point for autism. Greater levels of intellectual disability and visual loss were reported in children with ASD in comparison to those without ASD, but, of the two, intellectual disability was a better predictor for ASD. The SCQ lost its sensitivity and specificity in children who had greater visual loss which highlights a requirement for a measure that is sensitive to visual loss. It is also recommended that children with SOD/ONH would benefit from routine screening for ASDs. © 2013 Elsevier Ltd.

Item Type: Article
Uncontrolled Keywords: Autism, Autistic spectrum disorders, Blindness, Hypopituitarism, Optic nerve hypoplasia, Septo-optic dysplasia, Visual impairment, adolescent, article, autism, child, clinical article, cross-sectional study, disease association, female, human, hypopituitarism, intellectual impairment, male, optic nerve hypoplasia, prediction, preschool child, questionnaire, school child, sensitivity and specificity, septooptic dysplasia, social communication questionnaire, visual impairment, Autism, Autistic spectrum disorders, Blindness, Hypopituitarism, Optic nerve hypoplasia, Septo-optic dysplasia, Visual impairment, Adolescent, Autistic Disorder, Child, Child Development Disorders, Pervasive, Child, Preschool, Cross-Sectional Studies, Female, Humans, Hypopituitarism, Male, Optic Nerve Diseases, Sensitivity and Specificity, Septo-Optic Dysplasia
Subjects: A300 Clinical Medicine
Divisions: UoA Collections > UoA23: Sociology
Faculty of Business, Law and Social Sciences > School of Social Sciences > Dept. Criminology and Sociology
Depositing User: Hussen Farooq
Date Deposited: 14 Feb 2017 14:04
Last Modified: 14 Feb 2017 14:04
URI: http://www.open-access.bcu.ac.uk/id/eprint/2570

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