Diagnosis and Surveillance of Barrett's Esophagus: Addressing the Transatlantic Divide

Ghaus, S. and Neumann, H. and Muhammad, H. and Tontini, G.E. and Ishaq, S. (2016) Diagnosis and Surveillance of Barrett's Esophagus: Addressing the Transatlantic Divide. Digestive Diseases and Sciences, 61 (8). pp. 2185-2193. ISSN 01632116 (ISSN)

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Background: Barrett's esophagus is a premalignant condition of the esophagus leading to esophageal adenocarcinoma. No consensus exists between the UK and USA concerning the diagnosis of Barrett's esophagus. Although the diagnostic procedure is common, the required findings and diagnostic criteria vary. Both guidelines require endoscopy showing columnar epithelia lining the esophagus, but the US guidelines require the additional finding of intestinal metaplasia on biopsy to confirm diagnosis. Achievement of a consensus is of particular importance due to the established progression from Barrett's esophagus to esophageal adenocarcinoma. Of further importance is the increasing incidence of esophageal adenocarcinoma, a condition with poor overall survival, leading to various opinions on the utility of surveillance in patients. Discussion: A review of the vast array of literature revealed that substantial evidence exists in favor of both diagnostic criteria; hence, there is no easy way to identify the "correct" method of diagnosing Barrett's esophagus. USA recommends surveillance of Barrett's esophagus, whereas UK does not advocate it unless dysplasia is present. Surveillance was found to be effective, but this varied as did cost-effectiveness. Summary: Further research into diagnostic methods for Barrett's esophagus is needed to address areas of limited understanding, such that agreement can be reached and practice standardized. Surveillance was generally advocated, but with different criteria and time intervals, and new methods are being evaluated. © 2016 Springer Science+Business Media New York

Item Type: Article
Identification Number: https://doi.org/10.1007/s10620-016-4138-x
1 August 2016Published
1 April 2016Published Online
Uncontrolled Keywords: Barrett's esophagus, Diagnosis, Endoscopy, Intestinal metaplasia, Surveillance
Subjects: CAH01 - medicine and dentistry > CAH01-01 - medicine and dentistry > CAH01-01-01 - medical sciences (non-specific)
Divisions: Faculty of Health, Education and Life Sciences > School of Nursing and Midwifery
Depositing User: Users 18 not found.
Date Deposited: 08 Nov 2016 11:44
Last Modified: 03 Mar 2022 15:37
URI: https://www.open-access.bcu.ac.uk/id/eprint/497

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