Prioritizing treatment outcomes: How people with acne vulgaris decide if their treatment is working

Layton, A and Whitehouse, H and Eady, E.A and Cowdell, Fiona and Warburton, K and Fenton, M (2017) Prioritizing treatment outcomes: How people with acne vulgaris decide if their treatment is working. Journal of Evidence-Based Medicine, 10 (3). pp. 163-170. ISSN 1756-5383

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Abstract

Aim: To collect information about how people with acne make day-to-day decisions
concerning the effectiveness of their treatment.
Methods: Between May and August 2013, an optional question was embedded in
the James Lind Alliance Acne Priority Setting Partnership’s online survey to collect
treatment uncertainties. The question asked people with acne to ‘Tell us in your own
words how you decide if your treatment has been effective’.
Results: A total of 742 respondents specified at least one outcome or means of
assessing change (outcome measure). Fewer spots was the most commonly cited
outcome, identified by 272 respondents (36.7%). Other frequently mentioned
outcomes were, in descending order: less redness (19.4%), reduction in spot size
(12.1%) and less pain/discomfort (11.4%). Signs were much more commonly used
than symptoms and surrogate outcomes such as changes in aspects of life quality
were infrequently mentioned. Visual inspection of the skin was the most widely
adopted outcome measure (16.3%).
Conclusions: Although the most frequently used methods map well onto the
outcome measures adopted in the majority of acne trials, namely physician-assessed
changes in lesion counts and global acne severity, people with acne often take into account several factors that cannot be assessed by a third party at a single point in
time. The minimal use of changes in psychosocial wellbeing and mood may reflect
that these are regarded as secondary consequences of improvements in
appearance. The robustness of these findings now requires independent evaluation.
If confirmed, they could form the basis of a new patient-reported outcome measure.

Item Type: Article
Subjects: B700 Nursing
Divisions: UoA Collections > REF2021 UoA 03: Allied Health Professions, Dentistry, Nursing & Pharmacy
Depositing User: Fiona Cowdell
Date Deposited: 24 Aug 2018 09:02
Last Modified: 24 Aug 2018 09:02
URI: http://www.open-access.bcu.ac.uk/id/eprint/6175

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