A study on EEG-based brain electrical source of mild depressed subjects
Li, X. and Hu, B. and Xu, T. and Shen, J. and Ratcliffe, M. (2015) A study on EEG-based brain electrical source of mild depressed subjects. Computer Methods and Programs in Biomedicine, 120 (3). pp. 135-141. ISSN 01692607 (ISSN)
Full text not available from this repository. (Request a copy)Abstract
Background and objective: Several abnormal brain regions are known to be linked to depression, including amygdala, orbitofrontal cortex (OFC), anterior cingulate cortex (ACC), and dorsolateral prefrontal cortex (DLPFC) etc. The aim of this study is to apply EEG (electroencephalogram) data analysis to investigate, with respect to mild depression, whether there exists dysregulation in these brain regions. Methods: EEG sources were assessed from 9 healthy and 9 mildly depressed subjects who were classified according to the Beck Depression Inventory (BDI) criteria. t-Test was used to calculate the eye movement data and standardized low resolution tomography (sLORETA) was used to correlate EEG activity. Results: A comparison of eye movement data between the healthy and mild depressed subjects exhibited that mildly depressed subjects spent more time viewing negative emotional faces. Comparison of the EEG from the two groups indicated higher theta activity in BA6 (Brodmann area) and higher alpha activity in BA38. Conclusions: EEG source location results suggested that temporal pole activity to be dysregulated, and eye-movement data analysis exhibited mild depressed subjects paid much more attention to negative face expressions, which is also in accordance with the results of EEG source location. © 2015 Elsevier Ireland Ltd.
| Item Type: | Article | ||||
|---|---|---|---|---|---|
| Identification Number: | https://doi.org/10.1016/j.cmpb.2015.04.009 | ||||
| Dates: |
|
||||
| Uncontrolled Keywords: | EEG, Eye movement, Mild depression, SLORETA, Bioelectric phenomena, Brain, Data handling, Electroencephalography, Information analysis, Anterior cingulate cortices, Beck depression inventories, Brain electrical sources, Dorsolateral prefrontal cortex, Eeg(electroencephalogram), Mild depression, Orbitofrontal cortices (OFC), SLORETA, Eye movements, adult, alpha rhythm, amygdaloid nucleus, anterior cingulate, Article, beta rhythm, brain region, clinical article, controlled study, delta rhythm, depression, dorsolateral prefrontal cortex, electroencephalogram, eye movement, facial expression, female, frontal lobe, hemodynamic monitoring, human, inferior temporal gyrus, inferior temporal lobe, male, middle frontal gyrus, orbital cortex, primary motor cortex, superior temporal gyrus, temporal gyrus, temporal lobe, transverse temporal gyrus | ||||
| Subjects: | CAH01 - medicine and dentistry > CAH01-01 - medicine and dentistry > CAH01-01-01 - medical sciences (non-specific) | ||||
| Divisions: | Faculty of Computing, Engineering and the Built Environment Faculty of Computing, Engineering and the Built Environment > School of Computing and Digital Technology |
||||
| Depositing User: | Yasser Nawaz | ||||
| Date Deposited: | 18 Jul 2016 10:00 | ||||
| Last Modified: | 22 Mar 2023 12:01 | ||||
| URI: | https://www.open-access.bcu.ac.uk/id/eprint/1790 |
Actions (login required)
 |
View Item |
Tools
Tools