Faecal shedding of SARS-CoV-2 from patients with asymptomatic and mild COVID-19 without gastrointestinal symptoms in Ghana

Aninagyei, Enoch and Ayivor-Djanie, Reuben and Gyamfi, Jones and Owuani, Theodore and Ameke, Selassie Louis and Kpeli, Grace Semabia and Agbogli, Hubert Kwame and Essandoh, Priscilla and Duedu, Kwabena (2024) Faecal shedding of SARS-CoV-2 from patients with asymptomatic and mild COVID-19 without gastrointestinal symptoms in Ghana. BMC Research Notes, 17 (1). ISSN 1756-0500

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Abstract

Objective
In this study, we sought to determine whether faecal shedding occurs among SARS-COV-2 positive Ghanaians, as reported elsewhere. Hence we assayed for SARS-COV-2 in the stools of 48 SARS-COV-2 confirmed patients at the Ho Municipal Hospital in Ghana.

Results
Of the 48 COVID-19 patients, 45 (93.8%) had positive tests for SARS-CoV-2 faecal shedding. About 60% reported no respiratory symptoms, while only 2% (1 patient) reported gastrointestinal (GI) symptoms in the form of nausea. Other symptoms reported included headache (57.9%), weakness (57.9%), cough (52.6%), blocked/runny nose (47.4%), fever (31.6%), sore throat (31.6%), and shortness of breath (21.1%). One person complained of nausea (5.3%) Semi-quantitative comparison of the SARS COV-2 viral loads in matched respiratory and faecal samples using the cycle threshold (CT) values revealed no statistical differences. Furthermore, the duration between collection of respiratory and faecal samples did not have any direct influence on the differences in the CT values. This suggests that treatment and use of sewage for environmental surveillance of SARS COV-2 could be a potential public health countermeasure.

Item Type: Article
Identification Number: https://doi.org/10.1186/s13104-024-06790-z
Dates:
DateEvent
29 April 2024Accepted
10 May 2024Published Online
Uncontrolled Keywords: COVID-19, SARS-CoV-2, Faecal shedding, Gastrointestinal symptoms, Sewage
Subjects: CAH03 - biological and sport sciences > CAH03-01 - biosciences > CAH03-01-01 - biosciences (non-specific)
Divisions: Faculty of Health, Education and Life Sciences > School of Health Sciences > Dept. Life Sciences
Depositing User: Gemma Tonks
Date Deposited: 10 May 2024 13:22
Last Modified: 10 May 2024 13:22
URI: https://www.open-access.bcu.ac.uk/id/eprint/15486

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