The association between low carbohydrate dietary score (LCDS) and cardiovascular risk factors: results from the Shiraz Heart Study (SHS)

Mosallanezhad, Zahra and Jalali, Mohammad and Clark, Cain and Zibaeenezhad, Mohammad Javad and Nouri, Mehran and Mohammadi, Seyyed Saeed and Sayadi, Mehrab and Razeghian-Jahromi, Iman and Parsa, Nader and Zibaeenejad, Fatemeh and Sohrabi, Zahra (2024) The association between low carbohydrate dietary score (LCDS) and cardiovascular risk factors: results from the Shiraz Heart Study (SHS). BMC Public Health, 24 (1). ISSN 1471-2458

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Abstract

Background

Cardiovascular disease (CVD) is a major cause of death and recent studies have highlighted the potential role of dietary carbohydrate indices in cardiovascular health. Given the controversial results in this field, the aim of this study was to investigate the association between low carbohydrate dietary score (LCDS) and CVD risk factors in a population of Iranian adults.
Methods

This cross-sectional study was conducted within the framework of the Shiraz Heart Study (SHS) including 1982 adults. The validated 168 items food frequency questionnaire (FFQ) was used to assess participants’ dietary intakes. To investigate the association between LCDS and cardiometabolic risk factors, logistic regression, was conducted.
Results

During 5 years of follow-up, a total of 1982 adults, with a mean age of 53.07 ± 8.38 years, were included to the analysis. The adjusted model based on known confounding factors (age, sex, smoking, physical activity, energy intake and body mass index) revealed a significant decrease in a body shape index (ABSI) (OR = 0.70, 95% CI= (0.50 to 0.98), P = 0.038) comparing highest LCDS tertile vs. the reference. In contrast, risk of hypertension (HTN), body mass index (BMI), waist-hip ratio (WHR), triglyceride (TG), total cholesterol (TC), low-density lipoprotein cholesterol (LDL-c), high-density lipoprotein cholesterol (HDL-c), atherogenic index of plasma (AIP), and fasting blood sugar (FBS) were not significantly associated with LCDS.
Conclusion

Current findings suggest that adherence to a low carbohydrate diet reduces ABSI, a main indicator of central obesity.

Item Type: Article
Identification Number: 10.1186/s12889-024-20106-7
Dates:
Date
Event
16 October 2024
Accepted
29 October 2024
Published Online
Uncontrolled Keywords: cardiovascular disease, low carbohydrate diet, nutrition, obesity, cohort study
Subjects: CAH03 - biological and sport sciences > CAH03-02 - sport and exercise sciences > CAH03-02-01 - sport and exercise sciences
Divisions: Faculty of Health, Education and Life Sciences > College of Life Sciences
Depositing User: Gemma Tonks
Date Deposited: 23 Dec 2024 15:05
Last Modified: 23 Dec 2024 15:05
URI: https://www.open-access.bcu.ac.uk/id/eprint/16041

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